Yes, I pretty much skipped everything bar a few Stranger quests and went straight through the main story.
While it was a verrrry slow game, I still loved it, although it took until Ch4 until it really kicked off. I felt like Ch1 should have been shorter as it basically a tutorial, and then Ch2,3 and 4 condensed into one - it's main story is too long for what is a fairly straightforward plot. I can see why a fair few people didn't like it though, due to it's pacing. That, and it's a miserable tale of destruction; not one to play if you're teetering on the edge of depression....blimey
That being said, totally and completely blown away by it on a technical level. Unbelievable. The amount of VA, and the quality of it is outstanding.